Description

2-Fluorotoluene-Alpha,Alpha,α-D3 is a deuterated isotopologue of 2-fluorotoluene, where the three hydrogen atoms of the methyl group are replaced by deuterium. This compound is a critical reagent in advanced chemical research, offering a stable isotopic label for mechanistic studies and spectroscopic analysis. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for applications such as NMR spectroscopy, reaction pathway elucidation, and the synthesis of deuterated active pharmaceutical ingredients (APIs).

Application

• NMR Spectroscopy & Analytical Standards: Serves as an internal standard or a probe molecule in nuclear magnetic resonance (NMR) studies due to its distinct deuterium signature.
• Mechanistic Reaction Studies: Used as a tracer to investigate reaction mechanisms, kinetic isotope effects (KIE), and metabolic pathways in pharmaceutical development.
• Deuterated API Synthesis: Acts as a key building block in the synthesis of deuterium-labeled drug candidates to enhance metabolic stability and pharmacokinetic profiles.
• Mass Spectrometry: Employed as a labeled standard in mass spectrometry for accurate quantification and detection in complex matrices.
• Organic Electronics & Material Science: Used in the research and development of deuterated organic semiconductors and specialty polymers where isotopic purity affects material properties.
• Catalysis Research: A valuable tool for studying hydrogen/deuterium exchange reactions and catalyst behavior in fluorinated aromatic systems.

Basic Information

Product Name	2-Fluorotoluene-Alpha,Alpha,α-D3
CAS No.	25319-49-7
Molecular Formula	C7H4D3F
Molecular Weight	115.15 g/mol
Synonyms	2-Fluoro-α,α,α-trideuteriotoluene; 2-Methyl-α,α,α-trideuterofluorobenzene; o-Fluorotoluene-d3; 1-Fluoro-2-(trideuteriomethyl)benzene; Benzene, 1-fluoro-2-(trideuteriomethyl)-; 2-Fluorobenzyl-d3; o-Fluorotoluene-α,α,α-d3; 2-FT-d3
EINECS	Contact for details

Quality Control

Every batch of 2-Fluorotoluene-Alpha,Alpha,α-D3 is produced and analyzed under strict quality management protocols. We guarantee high chemical and isotopic purity, with comprehensive testing including assay, isotopic enrichment (D atom %), and impurity profiling. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed and upright to minimize loss and prevent contamination. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR/NMR)	Conforms to structure
Assay (GC)	≥ 98.0%
Isotopic Purity (D atom %)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	≤ 1.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.