Description

Phenolphthalein Complexone is a high-purity, specialized chelating agent and metallochromic indicator derived from phenolphthalein. This compound is valued for its exceptional selectivity and sensitivity in complexometric titrations, particularly for calcium and other alkaline earth metal ions. It is an essential analytical reagent for quality control and research laboratories in the pharmaceutical, water treatment, and chemical manufacturing industries. Our product ensures reliable performance and consistent results for critical analytical procedures.

Application

• Complexometric Titration Indicator: Primary use as a metallochromic indicator for the precise titration of calcium, barium, and magnesium ions with EDTA.
• Water Hardness Analysis: Key reagent in standard methods for determining total water hardness in industrial and municipal water treatment facilities.
• Pharmaceutical QC: Used in the assay and purity testing of calcium-containing active pharmaceutical ingredients (APIs) and formulations.
• Clinical Diagnostics: Employed in clinical chemistry kits for the colorimetric determination of calcium levels in biological fluids.
• Food & Beverage Testing: Applied in the analysis of mineral content, particularly calcium, in dairy products, fortified foods, and beverages.
• Research & Development: Serves as a selective chelator in biochemical and environmental research studies involving metal ion speciation.

Basic Information

Product Name	Phenolphthalein Complexone
CAS No.	25296-54-2
Molecular Formula	C30H26N2O13
Molecular Weight	622.54 g/mol
Synonyms	3,3'-Bis[N,N-bis(carboxymethyl)aminomethyl]-o-cresolphthalein; o-Cresolphthalein Complexone; Phthalein Purple; CPC; Calcium Colorimetric Indicator; NSC 113992; Metalphthalein; Glycine, N,N'-[(3,3'-(3H-2,1-benzoxathiol-3-ylidene)bis[(6-hydroxy-5-methyl-3,1-phenylene)methylene]]bis[N-(carboxymethyl)-, S,S-dioxide
EINECS	Contact for details

Quality Control

Our Phenolphthalein Complexone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the stringent requirements for analytical reagent (AR) grade. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Heavy Metals (as Pb)	≤ 20 ppm
Calcium Sensitivity Test	Passes
Solubility (in Alkali)	Clear, purple solution

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.