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1-Bromo-4-Cyclohexylbenzene CAS NO 25109-28-8


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CAS No.:25109-28-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-Bromo-4-Cyclohexylbenzene is a high-purity, versatile brominated aromatic intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring a cyclohexyl group para to a bromine atom, makes it a valuable building block for creating complex molecules with tailored properties. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials sectors seeking to develop new active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring lipophilic aromatic motifs.
  • Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the cyclohexylbenzene scaffold contributes to biological activity.
  • Liquid Crystal & OLED Materials: Acts as a fundamental building block for creating mesogenic cores and charge-transport materials in display and lighting technologies.
  • Ligand & Catalyst Development: Employed in the preparation of specialized phosphine or N-heterocyclic carbene (NHC) ligands for transition metal catalysis.
  • Polymer Modification: Utilized to introduce aromatic and bromine functional groups into polymer chains, altering thermal and mechanical properties.
  • Cross-Coupling Reactions: A reliable substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.

Basic Information

Product Name 1-Bromo-4-Cyclohexylbenzene
CAS No. 25109-28-8
Molecular Formula C₁₂H₁₅Br
Molecular Weight 239.15 g/mol
Synonyms 4-Bromophenylcyclohexane; p-Bromophenylcyclohexane; (4-Bromophenyl)cyclohexane; Cyclohexyl-4-bromobenzene; 1-Cyclohexyl-4-bromobenzene; 4-Cyclohexylbromobenzene; NSC 406913
EINECS Contact for details

Quality Control

Our 1-Bromo-4-Cyclohexylbenzene is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We are committed to meeting the stringent requirements of cGMP and ISO standards for our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item Specification
Appearance White to off-white crystalline solid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Melting Point Contact for details
Heavy Metals < 10 ppm
Residue on Ignition < 0.1%
Related Substances (HPLC) Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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