Description

5,5-Dibromo-6,7-Dihydro5H-Benzo[B]Thiophen-4-One is a high-purity brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which serves as a versatile precursor for the development of novel pharmaceuticals and functional materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Research: Used as a building block for synthesizing novel herbicides, fungicides, or insecticides, leveraging the bioactivity of the benzothiophene core.
• Material Science Precursor: Serves as a monomer or functional unit in the synthesis of organic semiconductors, conductive polymers, or advanced organic frameworks (MOFs/COFs).
• Dye and Pigment Synthesis: Employed in the production of specialized dyes and pigments where the dibromo-substituted structure imparts specific color and stability properties.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) due to the presence of bromine atoms, enabling rapid diversification of the molecular structure.
• Academic & Contract Research: A valuable reagent for universities and contract research organizations (CROs) exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	5,5-Dibromo-6,7-Dihydro5H-Benzo[B]Thiophen-4-One
CAS No.	25074-27-5
Molecular Formula	C8H6Br2OS
Molecular Weight	309.99 g/mol
Synonyms	5,5-Dibromo-4,5,6,7-tetrahydrobenzo[b]thiophen-4-one; 5,5-Dibromo-6,7-dihydro-4H-benzothiophen-4-one; 4H-Benzothiophen-4-one, 5,5-dibromo-6,7-dihydro-; 5,5-Dibromotetrahydrobenzothiophen-4-one; 5,5-Dibromo-4,5,6,7-tetrahydro-1-benzothiophen-4-one; 5,5-Dibromo-4,5,6,7-tetrahydrobenzo[b]thiophene-4-one
EINECS	Contact for details

Quality Control

Our 5,5-Dibromo-6,7-Dihydro5H-Benzo[B]Thiophen-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, handling should be performed under subdued light or in amber glass containers when possible.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.