Description

2-Nitroso-1,2,3,4-Tetrahydro-β-Carboline-3-Carboxylic Acid is a specialized heterocyclic organic compound featuring a nitroso group and a carboxylic acid moiety on a tetrahydro-β-carboline scaffold. This unique structure makes it a valuable advanced intermediate and research chemical for the synthesis of complex pharmacologically active molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel β-carboline alkaloid derivatives with potential neurological or anticancer activity.
• Biochemical Research: Used as a precursor or reference standard in studies investigating enzyme inhibition, receptor binding, or cellular signaling pathways.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug-like properties.
• Organic Synthesis: Employed in multi-step synthetic routes to create complex, polycyclic nitrogen-containing compounds.
• Academic Research: Utilized in university and institutional labs for chemical methodology development and the exploration of new heterocyclic chemistry.

Basic Information

Product Name	2-Nitroso-1,2,3,4-Tetrahydro-β-Carboline-3-Carboxylic Acid
CAS No.	24950-98-9
Molecular Formula	C₁₂H₁₁N₃O₃
Molecular Weight	245.24 g/mol
Synonyms	2-Nitroso-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid; 2-Nitroso-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylic acid; 3-Carboxy-2-nitroso-1,2,3,4-tetrahydro-β-carboline; 2-Nitroso-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid; NTCC; 2-Nitroso THCA
EINECS	Contact for details

Quality Control

Our 2-Nitroso-1,2,3,4-Tetrahydro-β-Carboline-3-Carboxylic Acid is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity and spectroscopic methods (NMR, IR) for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to orange powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.