Description

(1R,4S)-2-Azabicyclo[2.2.1]Heptane CAS NO 24875-04-5 is a high-purity, enantiomerically pure bicyclic amine, serving as a critical chiral building block in advanced organic synthesis. Its rigid, constrained structure is essential for imparting specific three-dimensional orientation and biological activity in target molecules. This compound is primarily required by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs), agrochemicals, and sophisticated ligands for catalysis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly for central nervous system (CNS) and antiviral therapeutics.
• Asymmetric Catalyst Ligand: Used to construct chiral ligands for transition metal catalysis, enabling enantioselective transformations in fine chemical production.
• Agrochemical Synthesis: Employed in the research and development of novel, enantiomerically pure pesticides and herbicides.
• Chemical Biology Probe: Utilized as a scaffold for developing molecular probes to study enzyme function and receptor interactions.
• Advanced Material Precursor: Acts as a building block for specialty polymers and functional materials requiring specific stereochemistry.

Basic Information

Product Name	(1R,4S)-2-Azabicyclo[2.2.1]Heptane
CAS No.	24875-04-5
Molecular Formula	C6H11N
Molecular Weight	97.16 g/mol
Synonyms	(1R,4S)-2-Azabicyclo[2.2.1]heptane; (1R,4S)-(-)-2-Azabicyclo[2.2.1]heptane; (-)-2-Azabicyclo[2.2.1]heptane; endo-(-)-2-Azabicyclo[2.2.1]heptane; (1R,4S)-2-Azanorbornane; 2-Azabicyclo[2.2.1]heptane, (1R,4S)-; L-2-Azabicyclo[2.2.1]heptane
EINECS	Contact for details

Quality Control

Our (1R,4S)-2-Azabicyclo[2.2.1]Heptane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Production adheres to cGMP guidelines where applicable, and each lot is supported by a comprehensive Certificate of Analysis (COA). The COA includes critical parameters such as chiral purity (HPLC), chemical purity (GC/HPLC), and residual solvent analysis, providing full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Purity (GC/HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.