Description

Tri(Phenyl-D5)Phosphine CAS NO 24762-44-5 is a deuterated organophosphorus compound where all hydrogen atoms on the phenyl rings are replaced with deuterium (D). This high-purity isotopically labeled reagent is essential for advanced research and development where precise tracking and minimal background interference are critical. It is primarily utilized by scientists and manufacturers in the pharmaceutical, agrochemical, and materials science industries for applications in NMR spectroscopy, reaction mechanism studies, and as a building block for labeled catalysts and ligands.

Application

• NMR Spectroscopy & Reaction Tracing: Serves as an internal standard or a probe in Nuclear Magnetic Resonance (NMR) studies to elucidate reaction mechanisms and kinetics without signal interference from protiated solvents or byproducts.
• Deuterated Catalyst & Ligand Synthesis: Acts as a key precursor for synthesizing deuterium-labeled phosphine ligands and catalysts used in homogeneous catalysis, enabling detailed mechanistic studies in hydrogenation and cross-coupling reactions.
• Pharmaceutical Research & Development: Employed in the synthesis of deuterated drug candidates and active pharmaceutical ingredients (APIs) for metabolic stability studies and to improve pharmacokinetic profiles.
• Mass Spectrometry Standards: Used as a stable isotope-labeled standard in quantitative mass spectrometry (MS) for accurate and sensitive detection and quantification in complex matrices.
• Advanced Materials Research: Utilized in the development of novel organic electronic materials and metal-organic frameworks (MOFs) where isotopic labeling is required to study structure-property relationships.
• Agrochemical Product Development: Applied in the synthesis of labeled agrochemicals to study environmental fate, degradation pathways, and metabolic processes in plants.

Basic Information

Product Name	Tri(Phenyl-D5)Phosphine
CAS No.	24762-44-5
Molecular Formula	C18D15P
Molecular Weight	274.33 g/mol
Synonyms	Triphenylphosphine-d15; Tris(pentadeuteriophenyl)phosphine; Phosphine, tris(pentadeuteriophenyl)-; Deuterated Triphenylphosphine; P(C6D5)3; TPP-d15; Triphenylphosphine-d15; (Penta-deuteriophenyl)phosphine
EINECS	Contact for details

Quality Control

Our Tri(Phenyl-D5)Phosphine is manufactured under strict quality control protocols to ensure high isotopic purity and chemical integrity, meeting the stringent requirements of research and industrial applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (D-atom %), chemical purity, and impurity profiles. We adhere to relevant industry standards and can provide material suitable for GMP/GLP-regulated environments upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at room temperature (15-25°C). This compound is easily oxidized and moisture-sensitive; prolonged exposure to air or light should be avoided to maintain purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Deuterium Enrichment (NMR)	≥ 98 atom % D
Assay (HPLC)	≥ 98.0%
Melting Point	78 - 82 °C
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.