Description

3-Bromoisoquinolin-1(2H)-One is a versatile brominated isoquinoline derivative, a crucial building block in advanced organic synthesis. Its value lies in its reactive bromine atom and fused heterocyclic structure, enabling the construction of complex molecules for pharmaceutical and material science research. This high-purity intermediate is essential for medicinal chemists and R&D laboratories developing novel active pharmaceutical ingredients (APIs) and functional organic materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential therapeutic agents, particularly in developing kinase inhibitors, anticancer compounds, and central nervous system (CNS) drugs.
• Agrochemical Research: Used in creating novel active ingredients for crop protection products, leveraging its heterocyclic scaffold.
• Material Science: Serves as a precursor for organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and other functional organic electronic materials.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry and the development of chemical tools for biological study.
• Academic & Industrial R&D: A fundamental reagent for methodological studies in cross-coupling reactions, such as Suzuki-Miyaura or Buchwald-Hartwig amination, and other metal-catalyzed transformations.

Basic Information

Product Name	3-Bromoisoquinolin-1(2H)-One
CAS No.	24623-16-3
Molecular Formula	C9H6BrNO
Molecular Weight	224.06 g/mol
Synonyms	3-Bromoisoquinolin-1(2H)-one; 3-Bromo-1(2H)-isoquinolinone; 3-Bromo-1,2-dihydroisoquinolin-1-one; 3-Bromoisoquinolin-1-ol; 1(2H)-Isoquinolinone, 3-bromo-; 3-Bromocarbostyril; 3-Bromo-1H-isoquinolin-1-one
EINECS	Contact for details

Quality Control

Our 3-Bromoisoquinolin-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.