Description

2H-1-Benzopyran-2-One, 8-Amino-7-Hydroxy-4-Methyl- is a functionalized coumarin derivative, a key heterocyclic compound valued for its role as a versatile synthetic intermediate. This compound matters for its ability to impart specific photophysical and biological properties to advanced materials and active pharmaceutical ingredients. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Fluorescent Probe & Dye Precursor: Used in the development of fluorescent markers, sensors, and imaging agents due to its coumarin core structure.
• Agrochemical Research: Serves as an intermediate in creating new active ingredients for crop protection products.
• Organic Synthesis & Material Science: A versatile synthon for constructing complex heterocyclic frameworks used in advanced organic electronic materials.
• Biochemical Research: Employed in studies involving enzyme inhibition, receptor binding, and other biological mechanisms.
• Fine Chemical Production: Used in the custom synthesis of specialty chemicals for various high-value industrial applications.

Basic Information

Product Name	2H-1-Benzopyran-2-One, 8-Amino-7-Hydroxy-4-Methyl-
CAS No.	24618-19-7
Molecular Formula	C10H9NO3
Molecular Weight	191.18 g/mol
Synonyms	8-Amino-7-hydroxy-4-methylcoumarin; 4-Methyl-7-hydroxy-8-aminocoumarin; 7-Hydroxy-8-amino-4-methylcoumarin; 8-Amino-7-hydroxy-4-methyl-2H-chromen-2-one; 4-Methylumbelliferone-8-amine; 8-Amino-4-methylumbelliferone; HAMC; 24618-19-7
EINECS	Contact for details

Quality Control

Our 2H-1-Benzopyran-2-One, 8-Amino-7-Hydroxy-4-Methyl- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters such as assay (HPLC), related substances, and physical characteristics. Our quality systems are designed to meet the stringent requirements of research and development as well as cGMP production environments for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to brownish powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Sparingly soluble in water; soluble in organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.