Description

Dimethyl [[(1-Oxoallyl)Amino]Methyl]Phosphonate is a specialized organophosphorus compound featuring a unique α-aminophosphonate structure with an enone functionality. This molecular architecture makes it a valuable intermediate for synthesizing complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, complex natural product analogs, and advanced material precursors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those containing phosphonate or α-amino acid motifs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators with potential phosphonate activity.
• Ligand and Catalyst Precursor: Serves as a starting material for creating specialized phosphonate-based ligands used in asymmetric catalysis and metal complexation.
• Peptidomimetic Research: Employed in the design and synthesis of peptidomimetics and protease inhibitors due to its hydrolytically stable phosphonate group mimicking a tetrahedral transition state.
• Material Science: Potential monomer or additive for creating specialty polymers with tailored properties like flame retardancy or metal chelation.
• Chemical Biology Probes: Useful for developing activity-based probes and enzyme inhibitors targeting hydrolases and transferases.

Basic Information

Product Name	Dimethyl [[(1-Oxoallyl)Amino]Methyl]Phosphonate
CAS No.	24610-95-5
Molecular Formula	C7H14NO4P
Molecular Weight	207.16 g/mol
Synonyms	Dimethyl (N-acryloylamino)methylphosphonate; Dimethyl [(acryloylamino)methyl]phosphonate; (Acryloylamino)methylphosphonic Acid Dimethyl Ester; Phosphonic Acid, P-[(1-Oxo-2-propen-1-yl)amino]methyl]-, Dimethyl Ester; N-(Dimethoxyphosphinylmethyl)acrylamide; Acrylamidomethylphosphonic Acid Dimethyl Ester
EINECS	Contact for details

Quality Control

Our Dimethyl [[(1-Oxoallyl)Amino]Methyl]Phosphonate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.