Description

Potassium Deuteroxide is the deuterated analog of potassium hydroxide, where the hydrogen atom in the hydroxide group is replaced by deuterium. This isotopic substitution makes it a critical reagent in the synthesis of deuterium-labeled compounds, which are essential for advanced research and analytical applications. It is primarily used as a strong base in organic synthesis and as a catalyst in specialized reactions where isotopic purity is required. Key industries that utilize this compound include pharmaceutical research, nuclear magnetic resonance (NMR) spectroscopy, and materials science.

Application

• Deuterium-Labeled Compound Synthesis: Acts as a key reagent for introducing deuterium atoms into organic molecules for use as internal standards in mass spectrometry and as tracers in metabolic studies.
• NMR Spectroscopy Solvent Preparation: Used in the preparation of deuterated solvents, such as deuterated dimethyl sulfoxide (DMSO-d6), which are essential for high-resolution NMR analysis.
• Catalysis in Organic Chemistry: Serves as a strong base catalyst in specialized organic reactions, including condensations and deuterium exchange reactions, where isotopic purity is paramount.
• Pharmaceutical Research & Development: Employed in the development and testing of deuterated drug candidates, which can offer improved metabolic stability and pharmacokinetic profiles.
• Materials Science Research: Utilized in the synthesis of advanced materials, including perovskites and other compounds, where isotopic control can influence physical properties.
• Analytical Chemistry Standards: Used to prepare calibration standards and reference materials for precise analytical measurements in isotopic analysis.

Basic Information

Product Name	Potassium Deuteroxide
CAS No.	24572-01-8
Molecular Formula	KOD
Molecular Weight	57.11 g/mol
Synonyms	Potassium Deuteroxide; Deuterated Potassium Hydroxide; Potassium Hydroxide-d; Potassium Deuteroxide Solution; KOD; Deuteropotassium Hydroxide; Potassium Monodeuteroxide; Deuterium Potassium Oxide
EINECS	Contact for details

Quality Control

Our Potassium Deuteroxide is produced and handled under stringent quality management protocols to ensure high isotopic purity and chemical consistency, which are critical for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (D-atom %), assay, and impurity profiles. We adhere to relevant industry standards for laboratory reagents, and specifications can be tailored to meet specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature and strong alkali properties, the container must be kept tightly sealed under an inert atmosphere (e.g., argon or nitrogen) to prevent absorption of atmospheric moisture and carbon dioxide. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid or solution
Identification (IR)	Conforms
Assay (KOD)	≥ 98.0 %
Deuterium Content (D-atom %)	≥ 99.0 %
Potassium Hydroxide (KOH)	≤ 1.0 %
Water Content (Karl Fischer)	≤ 0.5 %
Carbonate (as K2CO3)	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.