Description

Fumaric-2,3-D2 Acid CAS NO 24461-32-3 is a deuterium-labeled isotopologue of fumaric acid, a key intermediate in the Krebs cycle. This stable isotope-labeled compound is essential for advanced analytical and research applications where precise molecular tracking is required. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors for applications such as metabolic pathway studies, NMR spectroscopy, and as an internal standard in mass spectrometry.

Application

• Metabolic Research & Tracing: Used as a stable isotope tracer in biochemical studies to investigate the citric acid cycle and cellular respiration pathways.
• NMR Spectroscopy: Serves as a valuable analytical standard in Nuclear Magnetic Resonance (NMR) due to its deuterium labeling, aiding in structural elucidation and quantitative analysis.
• Mass Spectrometry Internal Standard: Employed as a high-purity internal standard in LC-MS and GC-MS methods for the accurate quantification of fumaric acid and related metabolites in complex matrices.
• Pharmaceutical Development: Used in the research and development of new drugs, particularly in pharmacokinetic and metabolic stability studies.
• Biochemical Reagent: Acts as a specialized reagent in enzymatic assays and other in-vitro biochemical experiments.
• Isotope Labeling Synthesis: Functions as a building block for the synthesis of more complex deuterium-labeled compounds for research purposes.

Basic Information

Product Name	Fumaric-2,3-D2 Acid
CAS No.	24461-32-3
Molecular Formula	C4H2D2O4
Molecular Weight	118.09 g/mol
Synonyms	(2E)-But-2-enedioic-2,3-d2 Acid; (E)-2-Butenedioic-2,3-d2 Acid; Deuterated Fumaric Acid; Fumaric Acid-d2; trans-1,2-Ethylenedicarboxylic-2,3-d2 Acid; Allomaleic-2,3-d2 Acid; Boletic-2,3-d2 Acid; Lichenic-2,3-d2 Acid
EINECS	Contact for details

Quality Control

Our Fumaric-2,3-D2 Acid is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high isotopic purity and chemical purity, meeting the exacting standards required for research and analytical applications. A comprehensive Certificate of Analysis (COA) detailing assay, isotopic enrichment, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Isotopic Purity (NMR/MS)	≥98 atom % D
Chemical Purity	≥95%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.