Description

3-Bromo-2-Nitrothiophene is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. Its unique molecular structure, featuring both bromo and nitro substituents on the thiophene ring, makes it a critical intermediate for constructing complex molecules with tailored electronic and pharmacological properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Organic Electronic Materials: Serves as a building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), field-effect transistors (OFETs), and solar cells.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Dye and Pigment Manufacturing: Intermediate for synthesizing specialized thiophene-based dyes and colorants.
• Academic and Industrial Research: Fundamental reagent for methodological studies in cross-coupling reactions, heterocyclic chemistry, and structure-activity relationship (SAR) exploration.

Basic Information

Product Name	3-Bromo-2-Nitrothiophene
CAS No.	24430-27-1
Molecular Formula	C4H2BrNO2S
Molecular Weight	208.03 g/mol
Synonyms	2-Nitro-3-bromothiophene; 3-Bromo-2-nitrothiophene; Thiophene, 3-bromo-2-nitro-; 3-Brom-2-nitrothiophen; 24430-27-1; 3-Bromo-2-nitro-thiophene; 3-Br-2-NO2-Thiophene
EINECS	Contact for details

Quality Control

Every batch of our 3-Bromo-2-Nitrothiophene is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Individual impurity ≤1.0%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.