Description

17,21-[(Butylboranediyl)Bis(Oxy)]-3α-Hydroxy-5β-Pregnan-20-One is a high-purity, specialized steroid derivative with a unique boronate ester functional group. This compound serves as a critical advanced pharmaceutical intermediate and a valuable research chemical for the development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in synthetic chemistry and process development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel steroid-based drugs and active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of new chemical entities.
• Process Chemistry: Serves as a reference standard and a starting material for optimizing synthetic routes in pilot-scale production.
• Biochemical Research: Potential tool compound for studying enzyme inhibition and receptor binding activities related to steroid pathways.
• Fine Chemical Synthesis: Intermediate for producing other complex, high-value boronate-containing organic molecules.

Basic Information

Product Name	17,21-[(Butylboranediyl)Bis(Oxy)]-3α-Hydroxy-5β-Pregnan-20-One
CAS No.	24376-80-5
Molecular Formula	C29H49BO4
Molecular Weight	472.51 g/mol
Synonyms	3α-Hydroxy-5β-pregnan-20-one 17,21-butylboronate; 5β-Pregnan-3α-ol-20-one, 17,21-(butylboranediyl)bis(oxy)-; Butylboronic acid cyclic ester with 3α,21-dihydroxy-5β-pregnan-20-one; 17,21-O-Butylboranediyl-3α-hydroxy-5β-pregnan-20-one; 3α-Hydroxy-5β-pregnan-20-one 17,21-butylboronate ester
EINECS	Contact for details

Quality Control

Our 17,21-[(Butylboranediyl)Bis(Oxy)]-3α-Hydroxy-5β-Pregnan-20-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets stringent specifications for research and pharmaceutical use. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.