Description

2-Butanone-1,1,1,3,3-D5 is a deuterated analog of methyl ethyl ketone (MEK), where five hydrogen atoms are replaced with deuterium, a stable isotope of hydrogen. This isotopic labeling makes it an essential tool for advanced analytical research, particularly in Nuclear Magnetic Resonance (NMR) spectroscopy and mass spectrometry, where it serves as an internal standard or solvent to eliminate background interference. It is primarily used by research scientists and analytical chemists in pharmaceutical development, metabolic studies, and materials science to obtain precise and reliable spectroscopic data.

Application

• NMR Spectroscopy Solvent: Used as a deuterated solvent for proton NMR, providing a non-interfering signal for accurate structural elucidation of organic compounds.
• Internal Standard for Mass Spectrometry: Acts as a precise reference standard in quantitative GC-MS and LC-MS analyses due to its distinct isotopic mass shift.
• Pharmaceutical Research & Development: Employed in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of drug molecules using isotopic tracing techniques.
• Polymer & Materials Science: Utilized in the analysis of polymer structures and dynamics, as well as in the study of reaction mechanisms where deuterium labeling is required.
• Chemical Synthesis Intermediate: Serves as a specialized building block in the synthesis of deuterated compounds for research purposes.

Basic Information

Product Name	2-Butanone-1,1,1,3,3-D5
CAS No.	24313-50-6
Molecular Formula	C4D5HO
Molecular Weight	77.13 g/mol
Synonyms	Deuterated Methyl Ethyl Ketone; MEK-d5; Butanone-d5; 3,3,4,4,4-Pentadeuterio-2-butanone; Ethyl Methyl Ketone-d5; 2-Oxobutane-1,1,1,3,3-d5; Methyl Ethyl Ketone (D5); Deuterated Butanone
EINECS	Contact for details

Quality Control

Every batch of our 2-Butanone-1,1,1,3,3-D5 is produced and tested under strict quality management systems. We guarantee high chemical and isotopic purity, with specifications typically meeting or exceeding the requirements for research-grade deuterated solvents. Certificates of Analysis (COA) are provided with each shipment, detailing key parameters such as isotopic enrichment (Atom % D), chemical purity, and NMR suitability. Our quality commitment ensures reliable performance in your most sensitive analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat and ignition sources. Due to its highly volatile nature, ensure containers are kept upright and sealed when not in use. Recommended storage temperature is 2-25°C.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms
Purity (GC)	≥ 99.0%
Isotopic Enrichment (Atom % D)	≥ 99.0%
Water Content (KF)	≤ 0.1%
NMR Solvent Suitability	Passes test

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.