Description

1,3,3-Tris(Trimethylsilyl)-1-Butyne is a specialized organosilicon compound featuring a unique combination of a terminal alkyne and multiple trimethylsilyl protecting groups. This molecular architecture makes it a valuable synthetic building block and reactive intermediate in advanced organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular frameworks.

Application

• Advanced Pharmaceutical Intermediates: Serves as a key precursor in the synthesis of complex drug candidates, particularly those requiring alkyne functionalization or silicon-containing moieties.
• Agrochemical Synthesis: Used in the research and development of novel active ingredients, where its protected alkyne group enables selective coupling reactions.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers, silicon-based coatings, and advanced hybrid materials.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for Sonogashira couplings, click chemistry, and other metal-catalyzed cross-coupling reactions.
• Ligand and Catalyst Development: Useful for preparing novel silicon-functionalized ligands for catalysis and organometallic chemistry applications.

Basic Information

Product Name	1,3,3-Tris(Trimethylsilyl)-1-Butyne
CAS No.	24295-78-1
Molecular Formula	C13H30Si3
Molecular Weight	270.65 g/mol
Synonyms	1-Butyne, 1,3,3-tris(trimethylsilyl)-; Tris(trimethylsilyl)butyne; 1,3,3-Tris(trimethylsilyl)but-1-yne; (Trimethylsilyl)ethynylbis(trimethylsilyl)methane; TMS-Protected Butyne Derivative
EINECS	Contact for details

Quality Control

Our production of 1,3,3-Tris(Trimethylsilyl)-1-Butyne adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, NMR, and FTIR analysis, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system is designed to support cGMP requirements for use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.