Description

5-Mercaptopyridine-3-Carboxylic Acid is a versatile heterocyclic building block featuring both a carboxylic acid and a thiol functional group on a pyridine scaffold. This bifunctional nature makes it a critical intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and material science industries for applications in drug discovery, ligand synthesis, and the creation of functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological disorders and cancers.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Ligand for Catalysis: Serves as a chelating agent or ligand precursor for transition metal catalysts used in cross-coupling and other organic transformations.
• Material Science Building Block: Incorporated into polymers and coordination frameworks to impart specific chemical or electronic properties.
• Bioconjugation Chemistry: The thiol group enables site-specific modification of proteins, peptides, and other biomolecules.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	5-Mercaptopyridine-3-Carboxylic Acid
CAS No.	24242-21-5
Molecular Formula	C6H5NO2S
Molecular Weight	155.17 g/mol
Synonyms	3-Carboxy-5-mercaptopyridine; 5-Mercaptonicotinic Acid; 3-Pyridinecarboxylic acid, 5-mercapto-; 5-Thiolnicotinic Acid; 5-Sulfanylpyridine-3-carboxylic acid; 5-Mercapto-3-pyridinecarboxylic acid; 5-MPCA
EINECS	Contact for details

Quality Control

Our 5-Mercaptopyridine-3-Carboxylic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.