Description

2-Amino-4,7-dihydro-5H-thieno[2,3-c]pyridine-3,6-dicarboxylic acid 6-ethyl ester 3-methyl ester is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound serves as a critical intermediate for the development of novel pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily sought after by R&D laboratories and pharmaceutical manufacturers engaged in the synthesis of complex heterocyclic compounds for drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or other therapeutic areas requiring complex fused-ring heterocycles.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new chemical entities with improved efficacy and safety profiles.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing more complex polycyclic frameworks through various cyclization and functional group transformation reactions.
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection products, leveraging its unique thienopyridine scaffold.
• Material Science Precursor: Can be utilized in the synthesis of specialty chemicals and functional materials, such as organic semiconductors or ligands for catalysis.

Basic Information

Product Name	2-Amino-4,7-dihydro-5H-thieno[2,3-c]pyridine-3,6-dicarboxylic acid 6-ethyl ester 3-methyl ester
CAS No.	24237-51-2
Molecular Formula	C13H16N2O4S
Molecular Weight	296.34 g/mol
Synonyms	6-Ethyl 3-methyl 2-amino-4,7-dihydro-5H-thieno[2,3-c]pyridine-3,6-dicarboxylate; Ethyl methyl 2-amino-4,7-dihydro-5H-thieno[2,3-c]pyridine-3,6-dicarboxylate; 2-Amino-4,7-dihydro-5H-thieno[2,3-c]pyridine-3,6-dicarboxylic acid ethyl methyl ester; 3,6-Dicarbethoxy-2-amino-4,7-dihydro-5H-thieno[2,3-c]pyridine (common misnomer); Thienopyridine diester intermediate; CAS 24237-51-2.
EINECS	Contact for details

Quality Control

Our production of 2-Amino-4,7-dihydro-5H-thieno[2,3-c]pyridine-3,6-dicarboxylic acid 6-ethyl ester 3-methyl ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to verify specifications. Our quality system is designed to support cGMP (current Good Manufacturing Practice) standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.