Description

6-Acetyl-2-Amino-4,5,6,7-Tetrahydro-Thieno[2,3-C]Pyridine-3-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its fused thienopyridine heterocyclic structure. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), offering significant value in medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting the production of novel therapeutic agents.

Application

• Key Intermediate in API Synthesis: Serves as a crucial precursor in the multi-step synthesis of complex drug candidates, particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Used extensively in research laboratories for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Precursor for Biologically Active Molecules: Its unique scaffold is valuable for constructing molecules with potential activity in neurological and cardiovascular therapeutic areas.
• Fine Chemical Manufacturing: Employed in cGMP and non-GMP production environments for scaling up candidate compounds from milligram to kilogram scale.
• Contract Research & Development (CRD): Supplied to CROs and CDMOs engaged in custom synthesis projects for pharmaceutical clients.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in API production.

Basic Information

Item	Detail
Product Name	6-Acetyl-2-Amino-4,5,6,7-Tetrahydro-Thieno[2,3-C]Pyridine-3-Carboxylic Acid Ethyl Ester
CAS No.	24237-43-2
Molecular Formula	C13H16N2O3S
Molecular Weight	280.34 g/mol
Synonyms	Ethyl 6-acetyl-2-amino-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate; 6-Acetyl-2-amino-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylic acid ethyl ester; 2-Amino-6-acetyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylic acid ethyl ester; Thieno[2,3-c]pyridine-3-carboxylic acid derivative; ATTPE; CAS 24237-43-2
EINECS	Contact for details

Quality Control

Our 6-Acetyl-2-Amino-4,5,6,7-Tetrahydro-Thieno[2,3-C]Pyridine-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light). Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.