Description

Calotropagenin is a bioactive steroidal aglycone derived from plants of the *Calotropis* genus. This compound serves as a crucial intermediate and reference standard in pharmaceutical research and natural product chemistry. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and phytochemical industries for drug discovery, analytical method development, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel steroidal drugs and bioactive molecules.
• Reference Standard: Used in analytical laboratories for the identification and quantification of calotropagenin and related compounds via HPLC, LC-MS, or TLC.
• Biochemical Research: Employed in pharmacological studies to investigate its biological activities, such as cytotoxic, anti-inflammatory, or cardiotonic effects.
• Natural Product Extraction & Isolation: Serves as a target compound for the standardization of plant extracts from *Calotropis procera* and *Calotropis gigantea*.
• Academic Research: Utilized in universities and research institutes for studies in phytochemistry, pharmacognosy, and synthetic organic chemistry.

Basic Information

Product Name	Calotropagenin
CAS No.	24211-64-1
Molecular Formula	C23H34O5
Molecular Weight	390.51 g/mol
Synonyms	(20S)-3β,14β-Dihydroxy-19-oxo-5α-card-20(22)-enolide; 3β,14-Dihydroxy-19-oxocard-20(22)-enolide; Calotropagenine; NSC 169854; Uscharidin aglycone
EINECS	Contact for details

Quality Control

Our Calotropagenin is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR). We provide a Certificate of Analysis (COA) with each shipment, detailing all critical quality parameters to ensure consistency and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.