Description

1-Chloro-4-Methylisoquinoline is a versatile and high-purity heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of complex molecules, offering a reactive site for further functionalization. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the isoquinoline scaffold.
• Material Science: Serves as a building block for creating specialized ligands, organic semiconductors, and photoactive materials.
• Academic & Contract Research: Essential reagent for method development, library synthesis, and exploring new chemical spaces in academic and CRO laboratories.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals and dyes.

Basic Information

Product Name	1-Chloro-4-Methylisoquinoline
CAS No.	24188-78-1
Molecular Formula	C10H8ClN
Molecular Weight	177.63 g/mol
Synonyms	4-Methyl-1-chloroisoquinoline; 1-Chloro-4-methyl-isoquinoline; Isoquinoline, 1-chloro-4-methyl-; 1-Chloro-4-methylisoquinoline; 4-Methylisoquinolin-1-yl chloride
EINECS	Contact for details

Quality Control

Our 1-Chloro-4-Methylisoquinoline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to meet the stringent requirements of research and development partners globally.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.