Description

5-Chloro-3-(2-Fluorophenyl)-1H-Indole-2-Carboxylic Acid is a high-purity, multi-functional indole derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique halogenated and fluorinated aromatic structure, which is essential for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging its halogenated indole core.
• Material Science: Serves as a monomer or functional additive in the research of advanced polymers and organic electronic materials.
• Biochemical Tool Compound: Employed in academic and industrial research as a probe or inhibitor to study specific enzymatic pathways and biological mechanisms.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring complex, fluorinated heterocyclic architectures.

Basic Information

Product Name	5-Chloro-3-(2-Fluorophenyl)-1H-Indole-2-Carboxylic Acid
CAS No.	24106-89-6
Molecular Formula	C15H9ClFNO2
Molecular Weight	289.69 g/mol
Synonyms	5-Chloro-3-(2-fluorophenyl)-1H-indole-2-carboxylic acid; 2-Fluorophenyl 5-chloroindole-2-carboxylate; 1H-Indole-2-carboxylic acid, 5-chloro-3-(2-fluorophenyl)-; 5-Chloro-3-(o-fluorophenyl)indole-2-carboxylic acid; 24106-89-6; AKOS005714555; ZINC19764295; SCHEMBL15450427
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-(2-Fluorophenyl)-1H-Indole-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.