Description

5-Chlorothiophene-2-Carboxylic Acid is a versatile heterocyclic building block of significant importance in modern synthetic chemistry. Its core value lies in its bifunctional structure, featuring both a reactive carboxylic acid group and a halogenated thiophene ring, enabling its use in the synthesis of complex molecules. This compound is primarily needed by R&D and production teams in the pharmaceutical, agrochemical, and material science industries for creating advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-infectives, and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the thiophene moiety contributes to biological activity.
• Material Science & Organic Electronics: Serves as a monomer or building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and semiconductors.
• Ligand & Catalyst Development: The carboxylic acid group allows for functionalization into amides, esters, and other derivatives used as ligands in catalytic systems or metal-organic frameworks (MOFs).
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new heterocyclic chemistry, synthesizing novel chemical libraries, and developing new synthetic methodologies.

Basic Information

Product Name	5-Chlorothiophene-2-Carboxylic Acid
CAS No.	24065-33-6
Molecular Formula	C5H3ClO2S
Molecular Weight	162.59 g/mol
Synonyms	2-Thiophenecarboxylic acid, 5-chloro-; 5-Chloro-2-thiophenecarboxylic acid; 5-Chloro-2-thiophene carboxylic acid; 5-Chlorothiophene-2-carboxylic acid; 2-Carboxy-5-chlorothiophene; 5-Chlorothiophene-2-carboxylate; 5-Chloro-2-thiophenecarboxylate; 5-Chloro-2-thiophenecarboxylic acid (CAS 24065-33-6)
EINECS	Contact for details

Quality Control

Our 5-Chlorothiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.