Description

Phenol-4-D1 is a deuterated derivative of phenol, where a hydrogen atom at the 4-position is replaced by a deuterium atom (CAS NO 23951-03-3). This isotopic labeling makes it an essential tool in advanced research and analytical chemistry, providing a stable, non-radioactive tracer. It is primarily used by scientists and manufacturers in the pharmaceutical, agrochemical, and material science industries for reaction mechanism studies, metabolic pathway tracing, and as an internal standard in quantitative mass spectrometry.

Application

• Pharmaceutical Research & Development: Used as a stable isotopic internal standard in LC-MS and GC-MS for the accurate quantification of phenol and its metabolites in biological samples.
• Metabolic Pathway Tracing: Serves as a deuterium-labeled tracer to study the biotransformation and pharmacokinetics of phenolic compounds in drug discovery.
• Mechanistic Studies: Employed in chemical reaction kinetics and mechanism elucidation, leveraging the kinetic isotope effect (KIE) of the carbon-deuterium bond.
• Polymer & Material Science: Acts as a labeled monomer or additive in the synthesis of specialized polymers for structural analysis and degradation studies.
• Environmental Analysis: Utilized as a reference standard in the detection and monitoring of phenolic pollutants in environmental samples.
• Agrochemical Development: Applied in the research of pesticides and herbicides to understand their environmental fate and metabolic breakdown.

Basic Information

Product Name	Phenol-4-D1
CAS No.	23951-03-3
Molecular Formula	C6H5DO
Molecular Weight	95.12 g/mol
Synonyms	4-Deuterophenol; Phenol-d1; [4-2H]Phenol; 4-Hydroxybenzene-d1; Phenol-4-d; Deuterated Phenol; 4-Deutero-1-hydroxybenzene; 4-D-Phenol
EINECS	Contact for details

Quality Control

Every batch of Phenol-4-D1 is produced and analyzed under strict quality management protocols. We ensure high chemical and isotopic purity, with specifications typically meeting or exceeding the requirements for research and analytical applications. Certificates of Analysis (COA) detailing parameters such as isotopic enrichment (D-atom %), chemical purity (by HPLC/GC), and identity confirmation (by NMR/MS) are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to handle under an inert atmosphere and minimize exposure to air and moisture for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR / NMR)	Conforms to structure
Isotopic Purity (D-atom %)	≥ 98%
Chemical Purity (HPLC/GC)	≥ 99%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.