Description

5,7-Dibromo-1,3-Dihydro-Indol-2-One is a halogenated indolinone derivative serving as a versatile and critical synthetic intermediate in advanced organic chemistry. Its value lies in its unique brominated structure, which facilitates selective coupling reactions and functional group transformations essential for constructing complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive scaffold.
• Material Science: Serves as a precursor for organic semiconductors, dyes, and photoactive compounds in electronic applications.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to introduce complex indole-based motifs.
• Academic & R&D: Utilized in university and industrial research laboratories for methodological studies and exploring new chemical spaces.
• Ligand & Catalyst Development: Acts as a starting material for synthesizing specialized ligands used in asymmetric catalysis.

Basic Information

Product Name	5,7-Dibromo-1,3-Dihydro-Indol-2-One
CAS No.	23872-19-7
Molecular Formula	C8H5Br2NO
Molecular Weight	298.94 g/mol
Synonyms	5,7-Dibromo-2-indolinone; 5,7-Dibromo-1,3-dihydro-2H-indol-2-one; 5,7-Dibromooxindole; 2-Oxo-5,7-dibromoindoline; 23872-19-7; 5,7-Dibromoindolin-2-one; AI3-52010; NSC 1631
EINECS	Contact for details

Quality Control

Our 5,7-Dibromo-1,3-Dihydro-Indol-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles for pharmaceutical-grade intermediates, ensuring traceability and documentation for regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.