Description

(3Z)-3-(Phenylmethylidene)-2,3-Dihydro-1H-Indol-2-One is a versatile synthetic intermediate belonging to the 3-alkylideneoxindole class of heterocyclic compounds. Its unique conjugated structure makes it a valuable building block for the synthesis of complex organic molecules with potential biological activity. This compound is primarily sought by research and development laboratories in the pharmaceutical and agrochemical sectors. It serves as a key precursor in medicinal chemistry for creating novel drug candidates targeting various disease pathways.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of bioactive molecules and potential drug candidates, particularly those with kinase inhibitory or anti-inflammatory properties.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic scaffold.
• Organic Synthesis Building Block: Employed in cyclization and cross-coupling reactions to construct more complex polycyclic frameworks common in natural products.
• Material Science Research: Investigated as a monomer or precursor for functional organic materials due to its π-conjugated system.
• Academic & R&D Laboratories: Serves as a standard reagent for methodological studies in synthetic organic chemistry and catalysis.

Basic Information

Product Name	(3Z)-3-(Phenylmethylidene)-2,3-Dihydro-1H-Indol-2-One
CAS No.	23772-61-4
Molecular Formula	C15H11NO
Molecular Weight	221.26 g/mol
Synonyms	3-Benzylideneindolin-2-one; (Z)-3-Benzylideneindolin-2-one; 3-Benzylidene-2-indolinone; Isatin 3-benzylidene; (3Z)-3-Benzylidene-1,3-dihydro-2H-indol-2-one; 23772-61-4; (Z)-3-Benzylidene-2-indolinone
EINECS	Contact for details

Quality Control

Our (3Z)-3-(Phenylmethylidene)-2,3-Dihydro-1H-Indol-2-One is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.