Description

Alletorphine is a potent, semi-synthetic opioid analgesic of the oripavine class, structurally related to etorphine. It is a high-value pharmaceutical reference standard and research chemical critical for advancing neuropharmacological studies. This compound is primarily utilized by pharmaceutical R&D laboratories, forensic science institutions, and academic researchers investigating opioid receptor mechanisms, analgesic pathways, and substance abuse.

Application

• Pharmaceutical Reference Standard: Used as a certified standard in analytical testing for method development, validation, and quality control of related pharmaceutical products.
• Neuroscience Research: Serves as a key tool compound in preclinical studies to investigate the binding affinity, efficacy, and selectivity at mu, delta, and kappa opioid receptors.
• Metabolic Pathway Studies: Employed in research to elucidate the metabolic fate, pharmacokinetics, and biotransformation pathways of potent opioids.
• Forensic Analysis: Acts as a critical analytical standard for the identification and quantification of controlled substances in forensic toxicology and law enforcement laboratories.
• Analytical Method Development: Utilized in the development and calibration of sophisticated analytical techniques such as HPLC-MS/MS and GC-MS for opioid detection.
• Pharmacological Profiling: Applied in vitro and in vivo to study the structure-activity relationships (SAR) of oripavine derivatives for potential therapeutic applications.

Basic Information

Product Name	Alletorphine
CAS No.	23758-80-7
Molecular Formula	C26H35NO5
Molecular Weight	441.56 g/mol
Synonyms	17-Allyl-7,8-dihydro-7α-[1-(R)-hydroxy-1-methylbutyl]-6,14-endo-etheno-6,7,8,14-tetrahydrooripavine; N-Allyl-7,8-dihydro-7α-[1-(R)-hydroxy-1-methylbutyl]-O6-methyl-6,14-endo-ethenonorthebaine; 17-Allyl-6,7,8,14-tetrahydro-7α-[1-(R)-hydroxy-1-methylbutyl]-6,14-endo-ethenooripavine; N-Allylnoretorphine; M-5050; Alletorfina; Allétorphine
EINECS	Contact for details

Quality Control

Our Alletorphine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including identification by spectroscopic methods (IR, NMR), purity assessment by HPLC, and residual solvent analysis to ensure it meets the stringent requirements for research and reference standards. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This material is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%
Assay (on dried basis)	97.0% - 102.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.