Description

(S)-(+)-3-(Benzyloxycarbonyl)-5-Oxo-4-Oxazolidineacetic Acid is a high-purity chiral building block and protected amino acid derivative essential for advanced organic synthesis. Its primary value lies in serving as a key intermediate for the preparation of complex, biologically active molecules, particularly in pharmaceutical research and development. This compound is critically needed by medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing novel drug candidates, especially those targeting protease inhibition and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of protease inhibitors, β-lactam antibiotics, and other active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis as a protected aspartic acid or glutamic acid analog for introducing specific stereochemistry.
• Asymmetric Synthesis: Serves as a starting material or auxiliary in asymmetric catalytic reactions to construct enantiomerically pure compounds.
• Bioconjugation & Probe Development: Utilized in the design and synthesis of chemical probes, enzyme substrates, and labeled compounds for biochemical research.
• Academic & Industrial R&D: Employed in research laboratories for method development and exploring new synthetic routes to complex heterocycles and natural product analogs.
• Custom Synthesis: A foundational block for contract research and manufacturing organizations (CROs/CMOs) producing custom fine chemicals for client projects.

Basic Information

Product Name	(S)-(+)-3-(Benzyloxycarbonyl)-5-Oxo-4-Oxazolidineacetic Acid
CAS No.	23632-66-8
Molecular Formula	C₁₄H₁₃NO₇
Molecular Weight	307.26 g/mol
Synonyms	(S)-3-(Benzyloxycarbonyl)-5-oxo-4-oxazolidineacetic acid; (S)-(+)-N-Carbobenzoxy-2,3-dehydro-2-aminosuccinic acid 4-lactone; Z-DHAS-OH; (S)-3-(Cbz)-5-oxo-4-oxazolidineacetic acid; (4S)-3-[(Benzyloxy)carbonyl]-5-oxo-1,3-oxazolidine-4-acetic acid; (S)-N-Cbz-dehydroaspartic acid β-lactone; 4-Oxazolidineacetic acid, 3-[(benzyloxy)carbonyl]-5-oxo-, (4S)-; Z-Asp(OBzl)-OH lactone
EINECS	Contact for details

Quality Control

Our (S)-(+)-3-(Benzyloxycarbonyl)-5-Oxo-4-Oxazolidineacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Specification available upon request
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.