Description

Pyrido[2,3-D]Pyridazine-5-D is a deuterated heterocyclic compound, a key building block in advanced pharmaceutical and agrochemical research. Its deuterium incorporation offers significant advantages in metabolic stability and pharmacokinetic profiling for new drug candidates. This high-value intermediate is essential for medicinal chemists and R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of deuterated drug candidates, particularly in oncology and CNS therapeutic areas.
• Metabolic Studies: Used as an internal standard or tracer in mass spectrometry for drug metabolism and pharmacokinetics (DMPK) studies.
• Agrochemical Research: Serves as a precursor in the development of novel, more stable pesticides and herbicides with improved environmental profiles.
• Material Science: Potential use in the synthesis of advanced organic electronic materials due to its fused heterocyclic structure.
• Isotope Labeling: Employed in mechanistic studies and reaction pathway elucidation within chemical synthesis.

Basic Information

Product Name	Pyrido[2,3-D]Pyridazine-5-D
CAS No.	23504-53-2
Molecular Formula	C7H3DN3
Molecular Weight	134.13 g/mol (for monodeuterated form)
Synonyms	5-Deuteropyrido[2,3-d]pyridazine; Pyrido[2,3-d]pyridazine-5-d1; 5-D-Pyrido[2,3-d]pyridazine; 1,2,4-Triazanaphthalene-5-d; Deuterated pyridopyridazine; [5-2H]Pyrido[2,3-d]pyridazine; 23504-53-2 (CAS); Light-sensitive pyridopyridazine derivative
EINECS	Contact for details

Quality Control

Our Pyrido[2,3-D]Pyridazine-5-D is manufactured under strict quality control protocols to ensure high chemical purity and isotopic enrichment. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as chemical purity (by HPLC), deuterium incorporation (by 1H NMR or MS), and impurity profile. We adhere to cGMP principles for advanced pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed under an inert atmosphere if possible to ensure long-term stability. Handle and store in accordance with all applicable laboratory safety regulations.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Incorporation	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.