Description

10-Methoxy-6-Methylergoline-8α-Carboxylic Acid Methyl Ester is a key ergoline alkaloid derivative, serving as a critical synthetic intermediate in the production of complex pharmaceutical compounds. Its value lies in its well-defined chemical structure, which provides a versatile scaffold for the development of active pharmaceutical ingredients (APIs) targeting neurological and cardiovascular systems. This high-purity intermediate is essential for research institutions and pharmaceutical manufacturers engaged in the synthesis and development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Primary use as a key building block in the multi-step synthesis of complex ergot alkaloid-derived APIs.
• Neurological Research: Used in the research and development of compounds targeting serotonin and dopamine receptor pathways.
• Cardiovascular Drug Synthesis: Serves as a precursor in the manufacture of medications for managing blood pressure and migraines.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial production of specialty pharmaceuticals.
• Academic & Contract Research: Fundamental material for synthetic chemistry research in academic and contract research organizations (CROs).

Basic Information

Product Name	10-Methoxy-6-Methylergoline-8α-Carboxylic Acid Methyl Ester
CAS No.	23495-66-1
Molecular Formula	C19H24N2O3
Molecular Weight	328.41 g/mol
Synonyms	Methyl 10-Methoxy-6-methyl-8α-ergolinecarboxylate; 10-Methoxy-6-methylergoline-8α-carboxylic acid methyl ester; 8α-Carbomethoxy-10-methoxy-6-methylergoline; 10-Methoxy-6-methyl-8α-ergolinecarboxylic acid methyl ester; Methyl 10-methoxy-6-methylergoline-8α-carboxylate; 23495-66-1; 10-Methoxy-6-methyl-8α-ergolinecarboxylate methyl ester
EINECS	Contact for details

Quality Control

Our 10-Methoxy-6-Methylergoline-8α-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical applications. Each lot undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.