Description

4-(Chloromethyl)-2-(4-Methoxyphenyl)-1,3-Thiazole Hydrochloride is a high-purity, functionalized thiazole derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and critical building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole core.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and photochromic materials due to its conjugated system.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes and enzyme mechanisms.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences sector.

Basic Information

Product Name	4-(Chloromethyl)-2-(4-Methoxyphenyl)-1,3-Thiazole Hydrochloride
CAS No.	23421-57-0
Molecular Formula	C11H11ClN2OS • HCl
Molecular Weight	275.15 g/mol (Free base: 238.73 g/mol)
Synonyms	2-(4-Methoxyphenyl)-4-(chloromethyl)thiazole Hydrochloride; 4-(Chloromethyl)-2-(p-methoxyphenyl)thiazole Hydrochloride; 1,3-Thiazole, 4-(chloromethyl)-2-(4-methoxyphenyl)-, hydrochloride; 2-(4-Methoxyphenyl)-4-(chloromethyl)-1,3-thiazole HCl; 4-Chloromethyl-2-(4-methoxyphenyl)thiazole Hydrochloride; p-Methoxyphenyl-4-chloromethylthiazole Hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(Chloromethyl)-2-(4-Methoxyphenyl)-1,3-Thiazole Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.