Description

D-Glucose-1,2,3,4,5,6,6-D7 is a stable isotope-labeled analog of D-glucose, where seven hydrogen atoms are replaced by deuterium, specifically at positions 1, 2, 3, 4, 5, 6, and 6. This high-purity labeled compound is essential as an internal standard for quantitative mass spectrometry, enabling precise and accurate metabolic flux analysis and biomarker discovery. It is a critical reagent for researchers and analytical laboratories in pharmaceutical development, clinical diagnostics, and metabolic research.

Application

• Quantitative Mass Spectrometry (MS): Serves as a stable isotope-labeled internal standard for the absolute quantification of glucose and its metabolites in complex biological matrices like plasma, serum, and cell lysates.
• Metabolic Flux Analysis (MFA): Used in 13C and 2H tracer studies to map and quantify pathways in central carbon metabolism, crucial for biotechnology and systems biology.
• Pharmaceutical Research & Drug Metabolism: Employed in pharmacokinetic (PK) and pharmacodynamic (PD) studies to track the metabolic fate of drug candidates and understand their mechanisms of action.
• Clinical Diagnostics & Biomarker Research: Facilitates the development of robust LC-MS/MS assays for measuring glucose and related analytes, aiding in the study of diabetes, cancer, and other metabolic disorders.
• NMR Spectroscopy: Acts as a deuterated standard or reference compound in nuclear magnetic resonance studies to simplify spectra and aid in structural elucidation.
• Food & Beverage Analysis: Applied in isotopic dilution methods for the accurate determination of sugar content and authenticity testing in food products.

Basic Information

Product Name	D-Glucose-1,2,3,4,5,6,6-D7
CAS No.	23403-54-5
Molecular Formula	C6H5D7O6
Molecular Weight	189.18 g/mol
Synonyms	D-Glucose-d7; Deuterated D-Glucose; [1,2,3,4,5,6,6-2H7]-D-Glucose; D-(+)-Glucose-1,2,3,4,5,6,6-d7; D-Glucose (1,2,3,4,5,6,6-D7); D-Glucose-d7; Hexose-d7; Dextrose-d7; Anhydrous Dextrose-d7; D-Glucopyranose-d7
EINECS	Contact for details

Quality Control

Every batch of D-Glucose-1,2,3,4,5,6,6-D7 is manufactured and analyzed under strict quality management systems. We ensure high chemical and isotopic purity through advanced analytical techniques including NMR, HPLC, and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing assay, isotopic enrichment, and impurity profiles is provided with each shipment to guarantee consistency and reliability for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Optical Rotation	+52.5° to +53.0° (c=10 in H2O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.