Description

(4S)-1,2,3,4-Tetrahydro-4-(4-Methoxyphenyl)-6,7-Dimethoxy-2-Methylisoquinoline is a high-purity chiral isoquinoline derivative, a critical building block in advanced pharmaceutical synthesis. Its defined stereochemistry and complex molecular architecture make it an essential intermediate for developing novel therapeutic agents. This compound is primarily utilized by research institutions and pharmaceutical manufacturers focused on central nervous system (CNS) drug discovery and other specialized medicinal chemistry applications.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential alkaloid-based pharmaceuticals and bioactive molecules.
• Neurological Research: Serves as a core scaffold for developing compounds targeting neurological receptors and pathways.
• Medicinal Chemistry R&D: Used in structure-activity relationship (SAR) studies and the creation of novel chemical libraries for high-throughput screening.
• Asymmetric Synthesis: Employed in chiral synthesis due to its defined (4S) stereocenter, enabling the production of enantiomerically pure targets.
• Reference Standard: Acts as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical analysis.
• Academic Research: Utilized in university and institutional labs for studying isoquinoline chemistry and its biological activities.

Basic Information

Product Name	(4S)-1,2,3,4-Tetrahydro-4-(4-Methoxyphenyl)-6,7-Dimethoxy-2-Methylisoquinoline
CAS No.	23367-60-4
Molecular Formula	C19H23NO3
Molecular Weight	313.39 g/mol
Synonyms	(S)-4-(4-Methoxyphenyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline; (4S)-4-(4-Methoxyphenyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-4-(4-methoxyphenyl)-6,7-dimethoxy-2-methylisoquinoline, (4S)-; NSC 163181; (S)-6,7-Dimethoxy-2-methyl-4-(4-methoxyphenyl)-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our (4S)-1,2,3,4-Tetrahydro-4-(4-Methoxyphenyl)-6,7-Dimethoxy-2-Methylisoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) providing identity, purity, and chiral excess data is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.