Description

(R)-(-)-1,2,3,4-Tetrahydro-1-Naphthol is a high-purity, chiral intermediate of significant importance in asymmetric synthesis. Its defined stereochemistry makes it a valuable building block for the production of enantiomerically pure pharmaceuticals and fine chemicals. This compound is essential for research and manufacturing in the pharmaceutical, agrochemical, and advanced materials sectors where precise molecular configuration is critical.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in cardiovascular and central nervous system (CNS) drug candidates.
• Asymmetric Catalyst Ligand Precursor: Used in the development and preparation of chiral ligands for transition metal catalysis.
• Agrochemical Synthesis: Serves as a building block for creating enantiopure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and process chemistry R&D.
• Material Science: Potential monomer or modifier in the synthesis of chiral polymers and advanced functional materials.

Basic Information

Product Name	(R)-(-)-1,2,3,4-Tetrahydro-1-Naphthol
CAS No.	23357-45-1
Molecular Formula	C10H12O
Molecular Weight	148.20 g/mol
Synonyms	(R)-1,2,3,4-Tetrahydro-1-naphthol; (R)-(-)-1,2,3,4-Tetrahydro-1-naphthalenol; (R)-1-Hydroxy-1,2,3,4-tetrahydronaphthalene; (R)-α-Tetralol; (R)-1-Tetralol; (R)-1,2,3,4-Tetrahydro-1-hydroxy-naphthalene; (R)-Tetrahydronaphth-1-ol
EINECS	Contact for details

Quality Control

Our (R)-(-)-1,2,3,4-Tetrahydro-1-Naphthol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.