Description

(4S)-1,2,3,4-Tetrahydro-4β-(4-Methoxyphenyl)-6,7-Dimethoxyisoquinoline is a chiral tetrahydroisoquinoline derivative, a key structural motif in medicinal chemistry. This compound matters as a versatile synthetic intermediate and a potential pharmacophore for developing new active pharmaceutical ingredients (APIs). Pharmaceutical research and development organizations need this high-purity building block for the synthesis of novel therapeutic agents targeting the central nervous system and other disease areas.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the multi-step synthesis of potential drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize biological activity.
• Alkaloid Synthesis: Acts as a precursor in the synthesis of complex natural product analogs and isoquinoline-based alkaloids.
• Asymmetric Catalysis Studies: Employed as a substrate or ligand in research focused on developing new chiral catalytic systems.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	(4S)-1,2,3,4-Tetrahydro-4β-(4-Methoxyphenyl)-6,7-Dimethoxyisoquinoline
CAS No.	23330-75-8
Molecular Formula	C19H23NO3
Molecular Weight	313.39 g/mol
Synonyms	(4S)-4-(4-Methoxyphenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; (S)-4-(4-Methoxyphenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; 4β-(4-Methoxyphenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline, (4S)-; Tetrahydroisoquinoline derivative 23330-75-8; (S)-THIQ derivative
EINECS	Contact for details

Quality Control

Our (4S)-1,2,3,4-Tetrahydro-4β-(4-Methoxyphenyl)-6,7-Dimethoxyisoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.