Description

2-Bromo-4-Methyl-1H-Imidazole is a halogenated heterocyclic building block of significant importance in advanced organic synthesis. This compound is valued for its reactivity, serving as a key precursor in the construction of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), functional materials, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial synthon for the development of novel drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced fungicides, herbicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a precursor for N-heterocyclic carbene (NHC) ligands and other organometallic catalysts.
• Material Science Research: Employed in the synthesis of organic electronic materials, ionic liquids, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for modifying peptides and proteins or creating activity-based probes for enzyme studies.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP or research-grade conditions.

Basic Information

Product Name	2-Bromo-4-Methyl-1H-Imidazole
CAS No.	23328-88-3
Molecular Formula	C4H5BrN2
Molecular Weight	161.00 g/mol
Synonyms	4-Methyl-2-bromoimidazole; 2-Bromo-4-methylimidazole; 2-Bromo-4-methyl-1H-imidazole; 4-Methyl-2-bromo-1H-imidazole; NSC 403914; 1H-Imidazole, 2-bromo-4-methyl-
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Methyl-1H-Imidazole is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We support development and commercial projects with material suitable for research, pilot plant, and cGMP manufacturing scales.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.