Description

Dehydroretrorsine is a pyrrolizidine alkaloid of significant interest in biochemical and pharmacological research. This compound serves as a critical reference standard and intermediate for studying hepatotoxicity and metabolic pathways. It is primarily utilized by research institutions, pharmaceutical development labs, and analytical testing facilities focused on natural product chemistry and toxicology. Our supply ensures high purity and batch-to-batch consistency for reliable experimental results.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the qualitative and quantitative analysis of pyrrolizidine alkaloids in herbal products and supplements.
• Toxicological Research: Employed in studies investigating the mechanisms of hepatotoxicity, genotoxicity, and metabolic activation of pyrrolizidine alkaloids.
• Biochemical Pathway Analysis: Serves as a key intermediate or inhibitor in research focused on liver enzyme metabolism and detoxification pathways.
• Quality Control & Method Development: Essential for developing and validating analytical methods (e.g., HPLC, LC-MS) in quality control laboratories for food, feed, and phytopharmaceuticals.
• Natural Product Isolation & Synthesis: Acts as a benchmark compound for the isolation, purification, and structural confirmation of related alkaloids from plant extracts.

Basic Information

Product Name	Dehydroretrorsine
CAS No.	23092-97-9
Molecular Formula	C18H23NO6
Molecular Weight	349.38 g/mol
Synonyms	Dehydroretrorsine; 12,18-Didehydro-7,21-dihydroxy-14,15-epoxy-13,19-didenecrotalanan-11,16-dione; (13Z)-13,19-Didehydro-12,18-epoxysenecionan-11,16-dione, 7,21-dihydroxy-; Retrorsine N-oxide derivative; DHR; Pyrrolizidine alkaloid PA
EINECS	Contact for details

Quality Control

Our Dehydroretrorsine is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR) and purity assessment by HPLC, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0 %
Residue on Ignition	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.