Description

4-Bromo-2-Nitrobenzyl Alcohol is a versatile aromatic building block characterized by its bromo and nitro substituents on the benzyl alcohol core. This compound is valued for its dual functionality, serving as a key intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), fine chemicals, and advanced material precursors.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its reactive sites for structural diversification.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the preparation of functionalized polymers and organic electronic materials due to its aromatic and electron-withdrawing groups.
• Dye and Pigment Intermediate: Acts as a building block for synthesizing nitro- and bromo-substituted colorants and photographic chemicals.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig aminations.

Basic Information

Item	Details
Product Name	4-Bromo-2-Nitrobenzyl Alcohol
CAS No.	22996-19-6
Molecular Formula	C7H6BrNO3
Molecular Weight	232.03 g/mol
Synonyms	2-Nitro-4-bromobenzyl alcohol; (4-Bromo-2-nitrophenyl)methanol; 4-Bromo-2-nitrobenzenemethanol; α-Hydroxy-4-bromo-2-nitrotoluene; BNBA; 4-Bromo-2-nitrobenzylalcohol
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Nitrobenzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.