Description

3,4-Di-tert-Butylthiophene is a high-purity, specialty organic compound belonging to the thiophene class, characterized by its sterically hindered tert-butyl substituents. This structural feature makes it a valuable intermediate and building block in advanced organic synthesis, particularly for creating complex molecules with tailored electronic and steric properties. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications requiring specific molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel active pharmaceutical ingredients (APIs), especially for compounds targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its bulky structure can influence biological activity and selectivity.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing specialized ligands in organometallic chemistry and catalysis, enabling more efficient and selective chemical transformations.
• Organic Electronic Materials: Investigated as a building block for π-conjugated systems in organic semiconductors, OLEDs, and other electronic materials due to the thiophene core.
• Polymer Modification: Employed to introduce functional thiophene units into polymer backbones, modifying properties like conductivity, thermal stability, and optical characteristics.
• Chemical Research & Development: A versatile reagent for method development and exploring new reaction pathways in academic and industrial research laboratories.

Basic Information

Product Name	3,4-Di-tert-Butylthiophene
CAS No.	22808-03-3
Molecular Formula	C12H20S
Molecular Weight	196.35 g/mol
Synonyms	3,4-Bis(1,1-dimethylethyl)thiophene; 3,4-Bis(tert-butyl)thiophene; 3,4-Di-t-butylthiophene; DTBT; NSC 163045; Thiophene, 3,4-bis(1,1-dimethylethyl)-; 3,4-Di-tert-butyl-thiophene
EINECS	Contact for details

Quality Control

Our 3,4-Di-tert-Butylthiophene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee consistent quality and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This compound is easily oxidized; ensure containers are sealed properly after each use to minimize exposure to air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0% (Area %)
Assay (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.