Description

Acetanilide-D8 CAS NO 22778-17-2 is a deuterated analog of acetanilide, where eight hydrogen atoms are replaced with deuterium, serving as a stable isotope-labeled internal standard. This high-purity compound is essential for ensuring accuracy and reliability in quantitative mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy analyses. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, agrochemical, and analytical chemistry sectors, enabling precise measurement and method validation.

Application

• Used as a stable isotope-labeled internal standard for the accurate quantification of acetanilide and related compounds in LC-MS and GC-MS methods.
• Critical for metabolite profiling and pharmacokinetic studies in pharmaceutical research and development.
• Enables deuterium NMR spectroscopy studies for structural elucidation and reaction mechanism analysis.
• Supports environmental analysis for tracing and quantifying aniline derivatives and their degradation products.
• Facilitates method development and validation in analytical laboratories to meet regulatory compliance (e.g., FDA, ICH guidelines).
• Employed in chemical synthesis research as a labeled precursor or tracer to study reaction pathways.

Basic Information

Product Name	Acetanilide-D8
CAS No.	22778-17-2
Molecular Formula	C8D8NO
Molecular Weight	141.23 g/mol
Synonyms	N-(Phenyl-d5)acetamide-d3; Acetanilide-d8; Deuterated Acetanilide; N-Phenylacetamide-d8; Acetic Acid (Phenyl-d5 Amide)-d3; Stable Isotope Labeled Acetanilide; [2H8]-Acetanilide; Internal Standard for Acetanilide
EINECS	Contact for details

Quality Control

Our Acetanilide-D8 is manufactured under strict quality control protocols to ensure exceptional isotopic purity and chemical integrity, essential for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment, chemical purity, and solvent content. We adhere to relevant industry standards to support GMP and GLP compliance in our customers' workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Purity (Deuterium Enrichment)	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.