Description

N,o-Bis(Trimethylsilyl)Hydroxylamine is a versatile organosilicon reagent primarily used as a protected hydroxylamine source in organic synthesis. This compound is critical for introducing the N-O functional group under mild conditions, enabling the synthesis of complex molecules. It is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity silylating agents for sensitive reactions.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for the preparation of protected hydroxylamines used in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Agrochemical Production: Employed in the manufacture of herbicides, fungicides, and insecticides where the introduction of an N-O moiety is required.
• Polymer & Material Science: Used as a functionalization agent or monomer in the development of specialty polymers and silicon-based advanced materials.
• Organic Synthesis Reagent: Acts as a versatile silylating agent and hydroxylamine equivalent in various name reactions and multi-step synthetic sequences.
• Chemical Research & Development: Essential tool for medicinal chemistry and process chemistry R&D for exploring new synthetic pathways.
• Fine Chemical Manufacturing: Utilized in the production of complex fine chemicals, flavors, and fragrances requiring specific functional group protection.

Basic Information

Product Name	N,o-Bis(Trimethylsilyl)Hydroxylamine
CAS No.	22737-37-7
Molecular Formula	C6H19NOSi2
Molecular Weight	177.40 g/mol
Synonyms	Bis(trimethylsilyl)hydroxylamine; O,N-Bis(trimethylsilyl)hydroxylamine; Hydroxylamine, O,N-bis(trimethylsilyl)-; N,O-Bis(trimethylsilyl)hydroxyamine; TMS-protected hydroxylamine; BSA-Hydroxylamine; (Trimethylsilyloxy)trimethylsilylamine
EINECS	Contact for details

Quality Control

Our N,o-Bis(Trimethylsilyl)Hydroxylamine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. Each lot undergoes comprehensive analytical testing, including chromatographic purity assessment and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.