Description

Phenyl-D5-Acetic Acid is a stable isotope-labeled analog of phenylacetic acid, where five hydrogen atoms on the phenyl ring are replaced with deuterium. This high-purity compound is essential for applications requiring precise internal standards and metabolic pathway tracing in advanced analytical techniques. It is a critical material for researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors who require reliable, isotopically pure building blocks for synthesis and quantification.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference standard in LC-MS and GC-MS analysis of pharmaceuticals and their metabolites.
• Metabolic Pathway Tracing: Employed in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of molecules in biological systems.
• Synthesis of Labeled Compounds: Serves as a key deuterated precursor for synthesizing more complex isotopically labeled active pharmaceutical ingredients (APIs).
• NMR Spectroscopy: Utilized as a solvent or reagent in nuclear magnetic resonance studies due to its deuterium content.
• Pharmaceutical Research: Critical for developing and validating bioanalytical methods in clinical and pre-clinical research.
• Environmental Analysis: Can be applied as a tracer in environmental fate studies of chemical compounds.

Basic Information

Product Name	Phenyl-D5-Acetic Acid
CAS No.	22705-26-6
Molecular Formula	C8D5H3O2
Molecular Weight	141.18 g/mol
Synonyms	(Phenyl-d5)acetic Acid; Deuterated Phenylacetic Acid; Phenylacetic-2,3,4,5,6-d5 Acid; Benzene-d5-acetic Acid; (2,3,4,5,6-Pentadeuteriophenyl)acetic Acid; α-Deuteriotoluic Acid (d5); PAA-d5
EINECS	Contact for details

Quality Control

Our Phenyl-D5-Acetic Acid is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity, which is paramount for analytical accuracy. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically ≥98 atom % D), chemical purity (by HPLC/NMR), and other critical parameters. We adhere to relevant industry standards for high-purity fine chemicals to guarantee batch-to-batch consistency and reliability for your most sensitive applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. The product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (NMR/MS)	≥98 atom % D
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.