Description

(3,5-2H2)-2H-Pyran-2-One CAS NO 22682-07-1 is a deuterated derivative of 2-pyrone, a valuable isotopically labeled building block for advanced chemical synthesis. This compound is essential for researchers and manufacturers requiring precise molecular probes with enhanced stability and distinct spectroscopic properties for analytical and diagnostic applications. It is primarily utilized in pharmaceutical research, agrochemical development, and academic studies involving reaction mechanism elucidation and metabolic pathway tracing.

Application

• Pharmaceutical Research & Development: As a deuterium-labeled intermediate in the synthesis of novel Active Pharmaceutical Ingredients (APIs) for pharmacokinetic (PK) and metabolic stability studies.
• Analytical Chemistry Standards: Serving as an internal standard or reference material in quantitative mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy for accurate compound identification and quantification.
• Mechanistic Studies: Used as a tracer to investigate chemical reaction pathways and mechanisms, leveraging the kinetic isotope effect (KIE) of deuterium.
• Agrochemical Development: Employed in the synthesis of labeled agrochemicals to study environmental fate, degradation pathways, and residue analysis.
• Material Science: As a precursor for developing specialized polymers or organic electronic materials where isotopic labeling can fine-tune properties.
• Contract Research & Manufacturing (CRMO): Supplied to organizations offering custom synthesis services for labeled compounds under GMP or ISO quality systems.

Basic Information

Product Name	(3,5-2H2)-2H-Pyran-2-One
CAS No.	22682-07-1
Molecular Formula	C5H4D2O2
Molecular Weight	100.11 g/mol
Synonyms	2H-Pyran-2-one-3,5-d2; Deuterated 2-Pyrone; 3,5-Dideutero-2H-pyran-2-one; 2-Pyrone-d2; 3,5-Dideutero-2-pyrone; α-Pyrone-d2; 2H-1-Benzopyran-2-one-3,5-d2 (incorrect but common mis-association); Isotopically Labeled 2-Pyrone
EINECS	Contact for details

Quality Control

Our (3,5-2H2)-2H-Pyran-2-One is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high isotopic purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chemical purity, isotopic enrichment (D-atom %), and impurity profile. We support development and commercial projects with specifications tailored to meet research, GLP, or cGMP requirements as needed.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to prevent moisture absorption and potential contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.