Description

3-Chloro-5,7-Dihydroxy-4-Methyl-2H-Chromen-2-One is a functionalized coumarin derivative, a key structural motif in organic synthesis and pharmaceutical research. This compound matters as a versatile synthetic intermediate for developing novel bioactive molecules, particularly in medicinal chemistry and material science. It is primarily needed by R&D chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for creating advanced chemical libraries and active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of novel drug candidates with potential anticoagulant, anti-inflammatory, or antimicrobial properties.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its coumarin core for biological activity.
• Fluorescent Probe Synthesis: Acts as a precursor for creating fluorescent dyes and molecular probes used in biochemical assays and diagnostics.
• Organic Light-Emitting Diode (OLED) Materials: Employed in research for developing electron-transport or emissive layers in organic electronic devices.
• Fine Chemical Synthesis: Utilized as a specialized intermediate for constructing complex natural product analogs and specialty chemicals.
• UV Absorber & Stabilizer Research: Investigated for potential use in polymer formulations to enhance light stability due to its chromen-2-one structure.

Basic Information

Product Name	3-Chloro-5,7-Dihydroxy-4-Methyl-2H-Chromen-2-One
CAS No.	22649-27-0
Molecular Formula	C10H7ClO4
Molecular Weight	226.61 g/mol
Synonyms	3-Chloro-5,7-dihydroxy-4-methylcoumarin; 5,7-Dihydroxy-3-chloro-4-methylcoumarin; 4-Methyl-3-chloro-5,7-dihydroxycoumarin; 3-Chloro-4-methyl-5,7-dihydroxy-2H-chromen-2-one; 3-Chloro-4-methylumbelliferone derivative; 22649-27-0; NSC 403714
EINECS	Contact for details

Quality Control

Our 3-Chloro-5,7-Dihydroxy-4-Methyl-2H-Chromen-2-One is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets precise customer specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation to maintain optimal purity and stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.