Description

4,6,7-Trihydroxycoumarin is a naturally derived polyphenolic compound belonging to the coumarin class, valued for its potent antioxidant and metal-chelating properties. This high-purity intermediate is critical for research and development in advanced material science and pharmaceutical synthesis. It serves as a key building block for scientists and manufacturers in the pharmaceutical, nutraceutical, and specialty chemical industries seeking to develop novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold for the synthesis of novel drug candidates with potential antioxidant, anti-inflammatory, or neuroprotective activities.
• Biochemical Research: Used as a standard or reagent in studies investigating oxidative stress, enzyme inhibition, and free radical scavenging mechanisms.
• Cosmetic & Skincare Actives: Incorporated into formulations for its antioxidant properties, helping to protect skin from environmental damage and support anti-aging claims.
• Nutraceutical Development: Explored as a bioactive ingredient in dietary supplements targeting cellular health and oxidative balance.
• Chemical Synthesis: Acts as a versatile precursor for the production of more complex coumarin derivatives and fluorophores used in analytical chemistry.
• Material Science: Investigated for use in developing functional polymers or coatings where antioxidant properties are desired.

Basic Information

Product Name	4,6,7-Trihydroxycoumarin
CAS No.	22649-24-7
Molecular Formula	C9H6O5
Molecular Weight	194.14 g/mol
Synonyms	4,6,7-Trihydroxy-2H-chromen-2-one; 4,6,7-Trihydroxycoumarin; 6,7-Dihydroxy-4-hydroxycoumarin; 4,6,7-Trihydroxy-1-benzopyran-2-one; Fraxetin; NSC 407347; 2H-1-Benzopyran-2-one, 4,6,7-trihydroxy-
EINECS	Contact for details

Quality Control

Our 4,6,7-Trihydroxycoumarin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, IR for identification, and residual solvent analysis to ensure it meets stringent specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, prolonged exposure to air should be minimized. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.