Description

3-[3-(4-Chlorophenyl)-1-(5-Chloro-2-Thienyl)-3-Oxopropyl]-4-Hydroxy-2-Benzopyrone is a high-purity, complex heterocyclic organic compound that serves as a critical advanced intermediate in modern synthetic chemistry. Its unique molecular architecture, featuring fused benzopyrone, chlorophenyl, and chlorothienyl moieties, makes it an essential building block for the development of novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought after by research institutions and industrial R&D departments focused on medicinal chemistry, agrochemical discovery, and material science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel therapeutic agents, particularly in research targeting anti-inflammatory, antimicrobial, or CNS-active compounds.
• Agrochemical Research: Used as a core scaffold for developing new-generation pesticides and herbicides, leveraging its chlorinated aromatic systems.
• Material Science: Serves as a monomer or functional additive in the development of specialty polymers and organic electronic materials due to its conjugated system.
• Chemical Synthesis: A versatile building block for constructing complex heterocyclic libraries in combinatorial chemistry and high-throughput screening.
• Academic & Industrial R&D: Fundamental research compound for studying structure-activity relationships (SAR) and novel organic reaction pathways.

Basic Information

Product Name	3-[3-(4-Chlorophenyl)-1-(5-Chloro-2-Thienyl)-3-Oxopropyl]-4-Hydroxy-2-Benzopyrone
CAS No.	22619-37-0
Molecular Formula	C22H14Cl2O4S
Molecular Weight	437.32 g/mol
Synonyms	4-Hydroxy-3-[3-(4-chlorophenyl)-1-(5-chloro-2-thienyl)-3-oxopropyl]-2H-1-benzopyran-2-one; 4-Hydroxy-3-[3-(4-chlorophenyl)-1-(5-chloro-2-thienyl)-3-oxopropyl]coumarin; 3-(3-(4-Chlorophenyl)-1-(5-chloro-2-thienyl)-3-oxopropyl)-4-hydroxy-2H-chromen-2-one; 22619-37-0; 4-Hydroxy-3-[3-(4-chlorophenyl)-1-(5-chloro-2-thienyl)propanoyl]coumarin; Chlorophenyl Chlorothienyl Oxopropyl Hydroxybenzopyrone
EINECS	Contact for details

Quality Control

Our production of 3-[3-(4-Chlorophenyl)-1-(5-Chloro-2-Thienyl)-3-Oxopropyl]-4-Hydroxy-2-Benzopyrone adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC-MS, and NMR for comprehensive characterization and impurity profiling. Certificates of Analysis (COA) detailing identity, purity, and related substances are provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.