Description

2,3-Dihydro-α,2-dioxo-1H-indole-3-acetic acid methyl ester is a versatile indole derivative and a key synthetic intermediate in organic chemistry. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those with indole-based structures.
• Agrochemical Research: Used in the development and production of advanced pesticides, herbicides, and plant growth regulators.
• Organic Synthesis: Serves as a key precursor in complex organic reactions, including cyclizations and functional group transformations, for academic and industrial research.
• Biochemical Research: Employed in the study of enzyme inhibitors and the development of biochemical probes and tools.
• Material Science: Potential intermediate in the synthesis of specialty polymers, dyes, and advanced organic materials.

Basic Information

Product Name	2,3-Dihydro-α,2-dioxo-1H-indole-3-acetic acid methyl ester
CAS No.	22600-51-7
Molecular Formula	C11H9NO4
Molecular Weight	219.19 g/mol
Synonyms	Methyl 2-(2,3-dihydro-2-oxo-1H-indol-3-yl)-2-oxoacetate; Methyl (2,3-dihydro-2-oxo-1H-indol-3-yl)oxoacetate; 1H-Indole-3-acetic acid, 2,3-dihydro-α,2-dioxo-, methyl ester; 3-(Methoxyoxalyl)indolin-2-one; Methyl 2-(2-oxoindolin-3-yl)-2-oxoacetate; N-Acetylisatin-3-carboxylic acid methyl ester (common name); Isatin-3-acetic acid methyl ester derivative
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-α,2-dioxo-1H-indole-3-acetic acid methyl ester is produced under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.