Description

1-Chloro-2-Pentyne is a halogenated alkyne building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a chlorine atom and a terminal alkyne group, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for applications such as cross-coupling reactions and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for introducing acetylene functionalities.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the chloroalkyne moiety is integral to biological activity.
• Cross-Coupling Reactions: Acts as a substrate in Sonogashira, Heck, and other palladium-catalyzed coupling reactions to form carbon-carbon bonds.
• Material Science Research: Employed in the development of polymers, dendrimers, and other functional materials with tailored properties.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands and organometallic catalysts used in homogeneous catalysis.
• Chemical Biology Probes: Facilitates the creation of tagged molecules and probes for studying biological systems via click chemistry.

Basic Information

Product Name	1-Chloro-2-Pentyne
CAS No.	22592-15-0
Molecular Formula	C5H7Cl
Molecular Weight	102.56 g/mol
Synonyms	2-Pentyn-1-yl chloride; Chloromethyl propyl acetylene; 1-Chloro-2-pentyne; 2-Pentynyl chloride; 1-Chloropent-2-yne; Propylchloroacetylene
EINECS	Contact for details

Quality Control

Our 1-Chloro-2-Pentyne is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for your synthetic workflows. Each lot undergoes comprehensive analytical testing, including purity assay and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong acids and bases. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.