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Lithium Triethylborohydride CAS NO 22560-16-3
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CAS No.:22560-16-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Lithium Triethylborohydride is a powerful and versatile superhydride reducing agent, commercially available as a solution in tetrahydrofuran or other suitable solvents. Its primary value lies in its exceptional reducing power and high selectivity, particularly for converting acid chlorides to aldehydes and for the stereoselective reduction of various functional groups. This reagent is essential for research and production in pharmaceutical synthesis, fine chemical manufacturing, and advanced material science, where precise and controlled reduction reactions are critical.
Application
- Pharmaceutical Intermediate Synthesis: Key reagent for the selective reduction of esters, lactones, and acid chlorides to aldehydes, a crucial step in API manufacturing.
- Asymmetric Synthesis: Employed in stereoselective reductions to produce chiral alcohols and other enantiomerically enriched compounds.
- Polymer Chemistry: Used as an initiator or catalyst in the polymerization of certain monomers and in the modification of polymer chains.
- Organic Synthesis Research: A staple reducing agent in laboratory-scale reactions for converting ketones to secondary alcohols and epoxides to alcohols with high regioselectivity.
- Fine Chemical Production: Applied in the synthesis of complex fragrances, flavors, and agrochemical intermediates requiring controlled reduction steps.
- Hydroboration Reactions: Serves as a source of hydride in hydroboration processes for functionalizing alkenes and alkynes.
Basic Information
| Item | Detail |
|---|---|
| Product Name | Lithium Triethylborohydride |
| CAS No. | 22560-16-3 |
| Molecular Formula | C6H16BLi |
| Molecular Weight | 105.94 g/mol |
| Synonyms | Lithium Triethylborohydride; Superhydride®; LiEt3BH; Lithium Triethylhydroborate; Triethylborohydride Lithium Salt; Lithium Hydrotriethylborate; 1-Lithio-2,2,2-triethylboranuide; Borate(1-), hydrotriethyl-, lithium (1:1) |
| EINECS | Contact for details |
Quality Control
Our Lithium Triethylborohydride solutions are produced under stringent conditions to ensure batch-to-batch consistency and high reactivity. Quality is verified through comprehensive analytical testing, including assay by titration and impurity profiling. A Certificate of Analysis (COA) detailing concentration, solvent, and specific test results is provided with each shipment to guarantee compliance with your research or production specifications.
Storage
Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C (refrigerated) due to its highly volatile and easily oxidized nature. The container must be kept tightly sealed in a cool, dry, well-ventilated area away from heat, sparks, and open flames. Allow the sealed container to reach room temperature before opening to minimize moisture ingress and pressure buildup.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to slightly yellow solution |
| Concentration (Typical) | 1.0 M in THF (or as specified) |
| Assay (Titration) | ≥ 95% |
| Identification (IR) | Conforms |
| Water Content (KF) | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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