Description

(1R,2R,3S,5R)-(-)-2,3-Pinanediol is a high-purity, chiral diol derivative of pinane, serving as a versatile and valuable building block in asymmetric synthesis. Its defined stereochemistry makes it a critical chiral auxiliary and resolving agent for the production of enantiomerically pure compounds. This product is essential for research and manufacturing in the pharmaceutical, agrochemical, and fine chemical industries, where precise stereocontrol is paramount.

Application

• Chiral Auxiliary in Asymmetric Synthesis: Used to induce stereoselectivity in a wide range of organic transformations, including aldol reactions and nucleophilic additions.
• Chiral Resolving Agent: Employed for the separation of racemic mixtures of acids, alcohols, and amines via diastereomeric salt or derivative formation.
• Pharmaceutical Intermediate: Serves as a key starting material or intermediate in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Ligand Precursor for Catalysis: Utilized in the preparation of chiral ligands for transition metal catalysts used in enantioselective hydrogenation and other catalytic processes.
• Agrochemical Synthesis: Applied in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fragrance and Flavor Chemistry: Acts as a chiral synthon for the production of stereodefined odorants and flavor compounds.

Basic Information

Product Name	(1R,2R,3S,5R)-(-)-2,3-Pinanediol
CAS No.	22422-34-0
Molecular Formula	C10H18O2
Molecular Weight	170.25 g/mol
Synonyms	(-)-2,3-Pinanediol; (1R,2R,3S,5R)-2,3-Dihydroxy-2,6,6-trimethylbicyclo[3.1.1]heptane; (1R,2R,3S,5R)-2,6,6-Trimethylbicyclo[3.1.1]heptane-2,3-diol; Pinanediol; trans-Pinanediol; L-Pinanediol
EINECS	Contact for details

Quality Control

Our (1R,2R,3S,5R)-(-)-2,3-Pinanediol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for stereochemical integrity and chemical purity. Certificates of Analysis (COA) detailing identity, assay, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent absorption of atmospheric moisture, which may affect product quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Specific Rotation [α]	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.